MMP-7 A-181G Polymorphism in Breast Cancer Patients from Western Iran

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MMP-7 A-181G Polymorphism in Breast Cancer Patients from Western Iran.

BACKGROUND Matrix metalloproteinases (MMPs) are upregulated in tumors. The MMP-7 A-181G polymorphism is associated with increased expression of the MMP-7 gene. Aim of the present study was to investigate the association between the MMP-7 A-181G polymorphism and susceptibility to breast cancer. PATIENTS AND METHODS The MMP-7 A-181G variants were studied in a cohort of 251 subjects consisting o...

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The variants of angiotensin converting enzyme (ACE) and matrix metalloproteinases (MMPs) genes might be involved in the pathogenesis of end stage renal disease (ESRD) and hypertension. We studied the ACE insertion/deletion (I/D) and MMP-7 A-181G variants in 99 unrelated ESRD patients and 117 individuals without renal complications from Western Iran with Kurdish ethnic background. The frequency ...

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ژورنال

عنوان ژورنال: Breast Care

سال: 2015

ISSN: 1661-3791,1661-3805

DOI: 10.1159/000442231